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Syndromes Grippaux

Depuis la semaine 2020s12 (mars 2020), il est demandé aux médecins Sentinelles de rapporter les cas d’ « Infections Respiratoires Aiguës (IRA) » vus en consultation de médecine générale et non plus les cas de « Syndromes grippaux », comme ce qui était fait depuis 1984. Grâce à une définition plus large, la surveillance des IRA permet d’étudier l'évolution de la pandémie de Covid-19 et des épidémies dues à d’autres virus respiratoires, dont la grippe.

Informations générales

A partir de la semaine 2020s12, les incidences de cet indicateur sont estimées secondairement à partir de l'indicateur Infections Respiratoires Aiguës. La comparaison des estimations des syndromes grippaux entre les périodes pré-Covid-19 (1984-février 2020) et post-Covid-19 (depuis mars 2020) doit donc se faire avec prudence.

    • Période de surveillance : 1984 - en cours
    • Résolution temporelle : Surveillance hebdomadaire
    • Rythme de publication : les données sont actualisées chaque mercredi
  • Définition des cas :
    Fièvre supérieure à 39°C, d'apparition brutale, accompagnée de myalgies et de signes respiratoires.
  • Données recueillies pour chaque cas : âge, sexe, réalisation et résultat d’un test diagnostic pour la COVID-19, réalisation d’un prélèvement dans le cadre de la surveillance virologique Sentinelles, statut vaccinal vis-à-vis de la COVID-19 et de la grippe, symptômes présentés, facteurs de risque de complications, demande d’hospitalisation ou de consultation aux urgences.
  • Changements impactant cet indicateur
    • 09/09/2020 Changement de la source des données

Pour visualiser ou télécharger les données Sentinelles, cliquez sur le bouton ci-dessous

Accès aux données Analyses historiques

Publications scientifiques associées à cette maladie
  • Greffe S, Guerrisi C, Souty C, Vilcu AM, Hayem G, Costantino F, Padovano I, Bourgault I, Trad S, Ponsoye M, Vilaine E, Debin M, Turbelin C, Blanchon T, Hanslik T. Influenza-like illness in individuals treated with immunosuppressants, biologics, and/or systemic corticosteroids for autoimmune or chronic inflammatory disease: A crowdsourced cohort study, France, 2017-2018. Influenza Other Respir Viruses. 2023. 17(6):e13148 PubMed 10.1111/irv.13148
  • Kissling E, Maurel M, Emborg HD, Whitaker H, McMenamin J, Howard J, Trebbien R, Watson C, Findlay B, Pozo F, Bolt Botnen A, Harvey C, Rose A, European IVE group, Members of the European IVE group. Interim 2022/23 influenza vaccine effectiveness: six European studies, October 2022 to January 2023. Euro Surveill. 2023. 28(21) PubMed PMC 10.2807/1560-7917.ES.2023.28.21.2300116
  • Kissling E, Pozo F, Martínez-Baz I, Buda S, Vilcu AM, Domegan L, Mazagatos C, Dijkstra F, Latorre-Margalef N, Kurečić Filipović S, Machado A, Lazar M, Casado I, Dürrwald R, van der Werf S, O'Donnell J, Linares Dopido JA, Meijer A, Riess M, Višekruna Vučina V, Rodrigues AP, Mihai ME, Castilla J, Goerlitz L, Falchi A, Connell J, Castrillejo D, Hooiveld M, Carnahan A, Ilić M, Guiomar R, Ivanciuc A, Maurel M, Omokanye A, Valenciano M, I-MOVE study team. Influenza vaccine effectiveness against influenza A subtypes in Europe: Results from the 2021-2022 I-MOVE primary care multicentre study. Influenza Other Respir Viruses. 2023. 17(1):e13069 PubMed PMC 10.1111/irv.13069
  • Liard R, Souty C, Guerrisi C, Colizza V, Hanslik T, Kengne Kuetche C, Turbelin C, Blanchon T, Debin M. Seasonal influenza vaccination in pharmacy in France: description and determinants of the vaccinated at-risk population using this service, 1 year after implementation. Int J Pharm Pract. 2022. 30(3):253-260 PubMed HAL 10.1093/ijpp/riac007
  • Kissling E, Hooiveld M, Brytting M, Vilcu AM, de Lange M, Martínez-Baz I, Sigerson D, Enkirch T, Belhillil S, Meijer A, Castilla J, William N, Carnahan A, Falchi A, Hendriksen J, Casado I, Murray J, Enouf V, Dijkstra F, Marques DFP, Valenciano M. Absence of association between 2019-20 influenza vaccination and COVID-19: Results of the European I-MOVE-COVID-19 primary care project, March-August 2020. Influenza Other Respir Viruses. 2021. 15(4):429-438 PubMed HAL 10.1111/irv.12839
  • Launay T, Souty C, Vilcu AM, Turbelin C, Blanchon T, Guerrisi C, Hanslik T, Colizza V, Bardoulat I, Lemaître M, Boëlle PY. Common communicable diseases in the general population in France during the COVID-19 pandemic. PLoS One. 2021. 16(10):e0258391 PubMed
  • Paternoster M, Masse S, van der Werf S, Lina B, Levy-Bruhl D, Villechenaud N, Valette M, Behillil S, Bernard-Stoecklin S, Guerrisi C, Blanchon T, Falchi A, Hanslik T, Turbelin C, Souty C. Estimation of influenza-attributable burden in primary care from season 2014/2015 to 2018/2019, France. Eur J Clin Microbiol Infect Dis. 2021. 40(6):1263-1269 PubMed HAL 10.1007/s10096-021-04161-1
  • Boëlle PY, Souty C, Launay T, Guerrisi C, Turbelin C, Behillil S, Enouf V, Poletto C, Lina B, van der Werf S, Lévy-Bruhl D, Colizza V, Hanslik T, Blanchon T. Excess cases of influenza-like illnesses synchronous with coronavirus disease (COVID-19) epidemic, France, March 2020. Euro Surveill. 2020. 25(14) PubMed HAL PMC 10.2807/1560-7917.ES.2020.25.14.2000326
  • Rose A, Kissling E, Emborg HD, Larrauri A, McMenamin J, Pozo F, Trebbien R, Mazagatos C, Whitaker H, Valenciano M, European IVE group.. Interim 2019/20 influenza vaccine effectiveness: six European studies, September 2019 to January 2020. Euro Surveill. 2020. 25(10) PubMed HAL PMC 10.2807/1560-7917.ES.2020.25.10.2000153
  • Guerrisi C, Ecollan M, Souty C, Rossignol L, Turbelin C, Debin M, Goronflot T, Boëlle PY, Hanslik T, Colizza V, Blanchon T. Factors associated with influenza-like-illness: a crowdsourced cohort study from 2012/13 to 2017/18. BMC Public Health. 2019. 19(1):879 PubMed HAL PMC 10.1186/s12889-019-7174-6
  • Kalimeri K, Delfino M, Cattuto C, Perrotta D, Colizza V, Guerrisi C, Turbelin C, Duggan J, Edmunds J, Obi C, Pebody R, Franco AO, Moreno Y, Meloni S, Koppeschaar C, Kjelsø C, Mexia R, Paolotti D. Unsupervised extraction of epidemic syndromes from participatory influenza surveillance self-reported symptoms. PLoS Comput Biol. 2019. 15(4):e1006173 PubMed HAL PMC 10.1371/journal.pcbi.1006173 Lien
  • Kissling E, Pozo F, Buda S, Vilcu AM, Gherasim A, Brytting M, Domegan L, Gómez V, Meijer A, Lazar M, Vučina VV, Dürrwald R, van der Werf S, Larrauri A, Enkirch T, O'Donnell J, Guiomar R, Hooiveld M, Petrović G, Stoian E, Penttinen P, Valenciano M, I-Move Primary Care Study Team. Low 2018/19 vaccine effectiveness against influenza A(H3N2) among 15-64-year-olds in Europe: exploration by birth cohort. Euro Surveill. 2019. 24(48) PubMed HAL PMC 10.2807/1560-7917.ES.2019.24.48.1900604
  • Kissling E, Pozo F, Buda S, Vilcu AM, Rizzo C, Gherasim A, Horváth JK, Brytting M, Domegan L, Meijer A, Paradowska-Stankiewicz I, Machado A, Vučina VV, Lazar M, Johansen K, Dürrwald R, van der Werf S, Bella A, Larrauri A, Ferenczi A, Zakikhany K, O'Donnell J, Dijkstra F, Bogusz J, Guiomar R, Filipović SK, Pitigoi D, Penttinen P, Valenciano M, I-MOVE/I-MOVE+ study team.. Effectiveness of influenza vaccine against influenza A in Europe in seasons of different A(H1N1)pdm09 and the same A(H3N2) vaccine components (2016-17 and 2017-18). Vaccine X. 2019. 3:100042 PubMed HAL PMC 10.1016/j.jvacx.2019.100042
  • Kissling E, Rose A, Emborg HD, Gherasim A, Pebody R, Pozo F, Trebbien R, Mazagatos C, Whitaker H, Valenciano M, European Ive Group. Interim 2018/19 influenza vaccine effectiveness: six European studies, October 2018 to January 2019. Euro Surveill. 2019. 24(8) PubMed HAL PMC 10.2807/1560-7917.ES.2019.24.1900121 Lien
  • Polyakov P, Souty C, Böelle PY, Breban R. Classification of Spatiotemporal Data for Epidemic Alert Systems: Monitoring Influenza-Like Illness in France. Am J Epidemiol. 2019. 188(4):724-733 PubMed HAL 10.1093/aje/kwy254
  • Souty C, Amoros P, Falchi A, Capai L, Bonmarin I, van der Werf S, Masse S, Turbelin C, Rossignol L, Vilcu AM, Lévy-Bruhl D, Lina B, Minodier L, Dorléans Y, Guerrisi C, Hanslik T, Blanchon T. Influenza epidemics observed in primary care from 1984 to 2017 in France: A decrease in epidemic size over time. Influenza Other Respir Viruses. 2019. 13(2):148-157 PubMed HAL PMC 10.1111/irv.12620 PDF
  • Souty C, Masse S, Valette M, Behillil S, Bonmarin I, Pino C, Turbelin C, Capai L, Vilcu AM, Lina B, van der Werf S, Blanchon T, Falchi A, Hanslik T. Baseline characteristics and clinical symptoms related to respiratory viruses identified among patients presenting with influenza-like illness in primary care. Clin Microbiol Infect. 2019. 25(9):1147-1153 PubMed HAL PMC 10.1016/j.cmi.2019.01.014
  • Adlhoch C, Snacken R, Melidou A, Ionescu S, Penttinen P, The European Influenza Surveillance Network. Dominant influenza A(H3N2) and B/Yamagata virus circulation in EU/EEA, 2016/17 and 2017/18 seasons, respectively. Euro Surveill. 2018. 23(13) PubMed PMC 10.2807/1560-7917.ES.2018.23.13.18-00146
  • Ariza M, Guerrisi C, Souty C, Rossignol L, Turbelin C, Hanslik T, Colizza V, Blanchon T. Healthcare-seeking behaviour in case of influenza-like illness in the French general population and factors associated with a GP consultation: an observational prospective study. BJGP Open. 2018. 1(4):bjgpopen17X101253 PubMed HAL PMC 10.3399/bjgpopen17X101253
  • Coletti P, Poletto C, Turbelin C, Blanchon T, Colizza V. Shifting patterns of seasonal influenza epidemics. Sci Rep. 2018. 8(1):12786 PubMed HAL PMC 10.1038/s41598-018-30949-x
  • Domenech de Cellès M, Arduin H, Varon E, Souty C, Boëlle PY, Lévy-Bruhl D, van der Werf S, Soulary JC, Guillemot D, Watier L, Opatowski L. Characterizing and Comparing the Seasonality of Influenza-Like Illnesses and Invasive Pneumococcal Diseases Using Seasonal Waveforms. Am J Epidemiol. 2018. 187(5):1029-1039 PubMed HAL 10.1093/aje/kwx336
  • Guerrisi C, Turbelin C, Souty C, Poletto C, Blanchon T, Hanslik T, Bonmarin I, Levy-Bruhl D, Colizza V. The potential value of crowdsourced surveillance systems in supplementing sentinel influenza networks: the case of France. Euro Surveill. 2018. 23(25) PubMed HAL PMC 10.2807/1560-7917.ES.2018.23.25.1700337
  • Hazard A, Bourrion B, Baltazard H, Fournier L, François M. Bénéfices et risques de la prescription d'un traitement homéopathique en prophylaxie antigrippale : exemple de l'influenzinum Exercer. 2018. 148:465-71 Lien PDF
  • Kissling E, Valenciano M, Pozo F, Vilcu AM, Reuss A, Rizzo C, Larrauri A, Horváth JK, Brytting M, Domegan L, Korczyńska M, Meijer A, Machado A, Ivanciuc A, Višekruna Vučina V, van der Werf S, Schweiger B, Bella A, Gherasim A, Ferenczi A, Zakikhany K, O Donnell J, Paradowska-Stankiewicz I, Dijkstra F, Guiomar R, Lazar M, Kurečić Filipović S, Johansen K, Moren A, I-MOVE/I-MOVE+ study team. 2015/16 I-MOVE/I-MOVE+ multicentre case-control study in Europe: Moderate vaccine effectiveness estimates against influenza A(H1N1)pdm09 and low estimates against lineage-mismatched influenza B among children. Influenza Other Respir Viruses. 2018. 12(4):423-437 PubMed HAL PMC 10.1111/irv.12520
  • Rondy M, Kissling E, Emborg HD, Gherasim A, Pebody R, Trebbien R, Pozo F, Larrauri A, McMenamin J, Valenciano M, I-Move/I-Move Group. Interim 2017/18 influenza seasonal vaccine effectiveness: combined results from five European studies. Euro Surveill. 2018. 23(9) PubMed HAL PMC 10.2807/1560-7917.ES.2018.23.9.18-00086
  • Souty C, Jreich R, LE Strat Y, Pelat C, Boëlle PY, Guerrisi C, Masse S, Blanchon T, Hanslik T, Turbelin C. Performances of statistical methods for the detection of seasonal influenza epidemics using a consensus-based gold standard. Epidemiol Infect. 2018. 146(2):168-176 PubMed HAL 10.1017/S095026881700276X
  • Valenciano M, Kissling E, Larrauri A, Nunes B, Pitigoi D, O'Donnell J, Reuss A, Horváth JK, Paradowska-Stankiewicz I, Rizzo C, Falchi A, Daviaud I, Brytting M, Meijer A, Kaic B, Gherasim A, Machado A, Ivanciuc A, Domegan L, Schweiger B, Ferenczi A, Korczyńska M, Bella A, Vilcu AM, Mosnier A, Zakikhany K, de Lange M, Kurečić Filipovićović S, Johansen K, Moren A, I-MOVE primary care multicentre case-control team.. Exploring the effect of previous inactivated influenza vaccination on seasonal influenza vaccine effectiveness against medically attended influenza: Results of the European I-MOVE multicentre test-negative case-control study, 2011/2012-2016/2017. Influenza Other Respir Viruses. 2018. 12(5):567-581 PubMed HAL PMC 10.1111/irv.12562
  • Vilcu AM, Souty C, Enouf V, Capai L, Turbelin C, Masse S, Behillil S, Valette M, Guerrisi C, Rossignol L, Blanchon T, Lina B, Hanslik T, Falchi A. Estimation of seasonal influenza vaccine effectiveness using data collected in primary care in France: comparison of the test-negative design and the screening method. Clin Microbiol Infect. 2018. 24(4):431.e5-431.e12 PubMed HAL 10.1016/j.cmi.2017.09.003
  • Flicoteaux R, Protopopescu C, Tibi A, Blanchon T, Werf SV, Duval X, Mosnier A, Charlois-Ou C, Lina B, Leport C, Chevret S. Factors associated with non-persistence to oral and inhaled antiviral therapies for seasonal influenza: a secondary analysis of a double-blind, multicentre, randomised clinical trial. BMJ Open. 2017. 7(7):e014546 PubMed HAL PMC 10.1136/bmjopen-2016-014546
  • Kissling E, Rondy M, I-MOVE/I-MOVE+ study team. Early 2016/17 vaccine effectiveness estimates against influenza A(H3N2): I-MOVE multicentre case control studies at primary care and hospital levels in Europe. Euro Surveill. 2017. 22(7) PubMed HAL PMC 10.2807/1560-7917.ES.2017.22.7.30464
  • Koppeschaar CE, Colizza V, Guerrisi C, Turbelin C, Duggan J, Edmunds WJ, Kjelsø C, Mexia R, Moreno Y, Meloni S, Paolotti D, Perrotta D, van Straten E, Franco AO. Influenzanet: Citizens Among 10 Countries Collaborating to Monitor Influenza in Europe. JMIR Public Health Surveill. 2017. 3(3):e58 PubMed HAL PMC 10.2196/publichealth.7429 Lien
  • Minodier L, Masse S, Capai L, Blanchon T, Ceccaldi PE, van der Werf S, Hanslik T, Charrel NR, Falchi A. Risk factors for seasonal influenza virus detection in stools of patients consulting in general practice for acute respiratory infections in France, 2014-2016. Influenza Other Respir Viruses. 2017. PubMed HAL PMC 10.1111/irv.12523
  • Minodier L, Masse S, Capai L, Blanchon T, Ceccaldi PE, van der Werf S, Hanslik T, Charrel R, Falchi A. Clinical and virological factors associated with gastrointestinal symptoms in patients with acute respiratory infection: a two-year prospective study in general practice medicine. BMC Infect Dis. 2017. 17(1):729 PubMed HAL PMC 10.1186/s12879-017-2823-9
  • Souty C, Vilcu AM, Capai L, van der Werf S, Valette M, Blanchon T, Lina B, Behillil S, Hanslik T, Falchi A. Early estimates of 2016/17 seasonal influenza vaccine effectiveness in primary care in France. J Clin Virol. 2017. 95:1-4 PubMed HAL 10.1016/j.jcv.2017.08.002
  • Guerrisi C, Turbelin C, Blanchon T, Hanslik T, Bonmarin I, Levy-Bruhl D, Perrotta D, Paolotti D, Smallenburg R, Koppeschaar C, Franco AO, Mexia R, Edmunds WJ, Sile B, Pebody R, van Straten E, Meloni S, Moreno Y, Duggan J, Kjelsø C, Colizza V. Participatory Syndromic Surveillance of Influenza in Europe. J Infect Dis. 2016. 214(suppl 4):S386-S392 PubMed 10.1093/infdis/jiw280
  • Loubet P, Guerrisi C, Turbelin C, Blondel B, Launay O, Bardou M, Blanchon T, Bonmarin I, Goffinet F, Ancel PY, Colizza V, Hanslik T, Kernéis S. First nationwide web-based surveillance system for influenza-like illness in pregnant women: participation and representativeness of the French G-GrippeNet cohort. BMC Public Health. 2016. 16(1):253 PubMed HAL PMC 10.1186/s12889-016-2899-y
  • Loubet P, Guerrisi C, Turbelin C, Blondel B, Launay O, Bardou M, Goffinet F, Colizza V, Hanslik T, Kernéis S, GGNET study group. Influenza during pregnancy: Incidence, vaccination coverage and attitudes toward vaccination in the French web-based cohort G-GrippeNet. Vaccine. 2016. 34(20):2390-6 PubMed 10.1016/j.vaccine.2016.03.034
  • Masse S, Minodier L, Heuze G, Blanchon T, Capai L, Falchi A. Influenza-like illness outbreaks in nursing homes in Corsica, France, 2014-2015: epidemiological and molecular characterization. Springerplus. 2016. 5(1):1338 PubMed HAL PMC 10.1186/s40064-016-2957-z
  • Souty C, Boëlle PY. Improving incidence estimation in practice-based sentinel surveillance networks using spatial variation in general practitioner density. BMC Med Res Methodol. 2016. 16(1):156 PubMed HAL PMC 10.1186/s12874-016-0260-x Lien
  • Spiga R, Batton-Hubert M, Sarazin M. Predicting Fluctuating Rates of Hospitalizations in Relation to Influenza Epidemics and Meteorological Factors. PLoS One. 2016. 11(6):e0157492 PubMed HAL PMC 10.1371/journal.pone.0157492
  • Blanchon T, Geffrier F, Turbelin C, Daviaud I, Laouénan C, Duval X, Lambert B, Hanslik T, Mosnier A, Leport C. Use of neuraminidase inhibitors in primary health care during pandemic and seasonal influenza between 2009 and 2013. Antivir Ther. 2015. 20(7):753-61 PubMed HAL PMC 10.3851/IMP2945
  • Boiron K, Sarazin M, Debin M, Raude J, Rossignol L, Guerrisi C, Odinkemelu D, Hanslik T, Colizza V, Blanchon T. Opinion about seasonal influenza vaccination among the general population 3 years after the A(H1N1)pdm2009 influenza pandemic. Vaccine. 2015. 33(48):6849-54 PubMed HAL 10.1016/j.vaccine.2015.08.067
  • Minodier L, Charrel RN, Ceccaldi PE, van der Werf S, Blanchon T, Hanslik T, Falchi A. Prevalence of gastrointestinal symptoms in patients with influenza, clinical significance, and pathophysiology of human influenza viruses in faecal samples: what do we know? Virol J. 2015. 12(1):215 PubMed HAL PMC 10.1186/s12985-015-0448-4
  • Souty C, Blanchon T, Bonmarin I, Lévy-Bruhl D, Behillil S, Enouf V, Valette M, Bouscambert M, Turbelin C, Capai L, Roussel V, Hanslik T, Falchi A. Early estimates of 2014/15 seasonal influenza vaccine effectiveness in preventing influenza-like illness in general practice using the screening method in France. Hum Vaccin Immunother. 2015. 11(7):1621-5 PubMed HAL PMC 10.1080/21645515.2015.1046661
  • Bajardi P, Vespignani A, Funk S, Eames KT, Edmunds WJ, Turbelin C, Debin M, Colizza V, Smallenburg R, Koppeschaar CE, Franco AO, Faustino V, Carnahan A, Rehn M, Paolotti D. Determinants of follow-up participation in the internet-based European influenza surveillance platform influenzanet. J Med Internet Res. 2014. 16(3):e78 PubMed HAL PMC 10.2196/jmir.3010
  • Cantarelli P, Debin M, Turbelin C, Poletto C, Blanchon T, Falchi A, Hanslik T, Bonmarin I, Levy-Bruhl D, Micheletti A, Paolotti D, Vespignani A, Edmunds J, Eames K, Smallenburg R, Koppeschaar C, Franco AO, Faustino V, Carnahan A, Rehn M, Colizza V. The representativeness of a European multi-center network for influenza-like-illness participatory surveillance. BMC Public Health. 2014. 14(1):984 PubMed HAL PMC 10.1186/1471-2458-14-984
  • Debin M, Colizza V, Blanchon T, Hanslik T, Turbelin C, Falchi A. Effectiveness of 2012-2013 influenza vaccine against influenza-like illness in general population: estimation in a French web-based cohort. Hum Vaccin Immunother. 2014. 10(3):536-43 PubMed HAL PMC 10.4161/hv.27439
  • Fantoni A, Arena C, Corrias L, Salez N, de Lamballerie X, Amoros JP, Blanchon T, Varesi L, Falchi A. Genetic drift of influenza A(H3N2) viruses during two consecutive seasons in 2011-2013 in Corsica, France. J Med Virol. 2014. 86(4):585-91 PubMed 10.1002/jmv.23745
  • Minodier L, Arena C, Heuze G, Ruello M, Amoros JP, Souty C, Varesi L, Falchi A. Epidemiology and Viral Etiology of the Influenza-Like Illness in Corsica during the 2012-2013 Winter: An Analysis of Several Sentinel Surveillance Systems. PLoS One. 2014. 9(6):e100388 PubMed HAL PMC 10.1371/journal.pone.0100388
  • Minodier L, Blanchon T, Souty C, Turbelin C, Leccia F, Varesi L, Falchi A. Influenza vaccine effectiveness: best practice and current limitations of the screening method and their implications for the clinic. Expert Rev Vaccines. 2014. 13(8):1039-48 PubMed 10.1586/14760584.2014.930666
  • Paolotti D, Carnahan A, Colizza V, Eames K, Edmunds J, Gomes G, Koppeschaar C, Rehn M, Smallenburg R, Turbelin C, Van Noort S, Vespignani A. Web-based participatory surveillance of infectious diseases: the Influenzanet participatory surveillance experience. Clin Microbiol Infect. 2014. 20(1):17-21 PubMed PMC 10.1111/1469-0691.12477
  • Souty C, Turbelin C, Blanchon T, Hanslik T, Le Strat Y, Boelle PY. Improving disease incidence estimates in primary care surveillance systems. Popul Health Metrics. 2014. 12(1):19 PubMed HAL PMC 10.1186/s12963-014-0019-8 Lien
  • Blanchon T, Mentré F, Charlois-Ou C, Dornic Q, Mosnier A, Bouscambert M, Carrat F, Duval X, Enouf V, Leport C, the Bivir Study Group. Factors associated with clinical and virological response in patients treated with oseltamivir or zanamivir for influenza A during the 2008-2009 winter. Clin Microbiol Infect. 2013. 19(2):196-203 PubMed HAL 10.1111/j.1469-0691.2011.03751.x
  • Debin M, Souty C, Turbelin C, Blanchon T, Boëlle PY, Hanslik T, Hejblum G, Le Strat Y, Quintus F, Falchi A. Determination of French influenza outbreaks periods between 1985 and 2011 through a web-based Delphi method. BMC Med Inform Decis Mak. 2013. 13(1):138 PubMed HAL PMC 10.1186/1472-6947-13-138
  • Debin M, Turbelin C, Blanchon T, Bonmarin I, Falchi A, Hanslik T, Levy-Bruhl D, Poletto C, Colizza V. Evaluating the feasibility and participants' representativeness of an online nationwide surveillance system for influenza in france. PLoS One. 2013. 8(9):e73675 PubMed HAL PMC 10.1371/journal.pone.0073675
  • Falchi A, Souty C, Grisoni ML, Mosnier A, Hanslik T, Daviaud I, Varesi L, Kerneis S, Carrat F, Blanchon T. Field seasonal influenza vaccine effectiveness: evaluation of the screening method using different sources of data during the 2010/2011 French influenza season. Hum Vaccin Immunother. 2013. 9(11):2453-9 PubMed PMC 10.4161/hv.25513
  • Pelat C, Lasserre A, Xavier A, Turbelin C, Blanchon T, Hanslik T. Hospitalization of influenza-like illness patients recommended by general practitioners in France between 1997 and 2010. Influenza Other Respi Viruses. 2013. 7(1):74-84 PubMed HAL PMC 10.1111/j.1750-2659.2012.00356.x
  • Privileggio L, Falchi A, Grisoni ML, Souty C, Turbelin C, Fonteneau L, Hanslik T, Kernéis S. Rates of immunization against pandemic and seasonal influenza in persons at high risk of severe influenza illness: a cross-sectional study among patients of the French Sentinelles general practitioners. BMC Public Health. 2013. 13(1):246 PubMed HAL PMC 10.1186/1471-2458-13-246
  • Turbelin C, Souty C, Pelat C, Hanslik T, Sarazin M, Blanchon T, Falchi A. Age Distribution of Influenza Like Illness Cases during Post-Pandemic A(H3N2): Comparison with the Twelve Previous Seasons, in France. PLoS One. 2013. 8(6):e65919 PubMed PMC 10.1371/journal.pone.0065919
  • Arena C, Amoros JP, Vaillant V, Balay K, Chikhi-Brachet R, Varesi L, Arrighi J, Blanchon T, Carrat F, Hanslik T, Falchi A. Simultaneous investigation of influenza and enteric viruses in the stools of adult patients consulting in general practice for acute diarrhea. Virol J. 2012. 9(1):116 PubMed HAL PMC 10.1186/1743-422X-9-116
  • Carrat F, Duval X, Tubach F, Mosnier A, van der Werf S, Tibi A, Blanchon T, Leport C, Flahault A, Mentré F, BIVIR study group. Effect of oseltamivir, zanamivir or oseltamivir-zanamivir combination treatments on transmission of influenza in households. Antivir Ther. 2012. 17(6):1085-90 PubMed 10.3851/IMP2128
  • Escuret V, Cornu C, Boutitie F, Enouf V, Mosnier A, Bouscambert-Duchamp M, Gaillard S, Duval X, Blanchon T, Leport C, Gueyffier F, van der Werf S, Lina B. Oseltamivir-zanamivir bitherapy compared to oseltamivir monotherapy in the treatment of pandemic 2009 influenza A(H1N1) virus infections. Antiviral Res. 2012. 96(2):130-7 PubMed HAL 10.1016/j.antiviral.2012.08.002
  • Boëlle PY, Ansart S, Cori A, Valleron AJ. Transmission parameters of the A/H1N1 (2009) influenza virus pandemic: a review. Influenza Other Respi Viruses. 2011. 5(5):306-16 PubMed PMC 10.1111/j.1750-2659.2011.00234.x
  • Falchi A, Amoros JP, Arena C, Arrighi J, Casabianca F, Andreoletti L, Turbelin C, Flahault A, Blanchon T, Hanslik T, Varesi L. Genetic structure of human A/H1N1 and A/H3N2 influenza virus on Corsica Island: phylogenetic analysis and vaccine strain match, 2006-2010. PLoS One. 2011. 6(9):e24471 PubMed HAL PMC 10.1371/journal.pone.0024471
  • Falchi A, Turbelin C, Andreoletti L, Arena C, Blanchon T, Bonmarin I, Hanslik T, Leruez-Ville M, De Lamballerie X, Carrat F. Nationwide surveillance of 18 respiratory viruses in patients with influenza-like illnesses: A pilot feasibility study in the French Sentinel Network. J Med Virol. 2011. 83(8):1451-7 PubMed HAL Peer 10.1002/jmv.22113
  • Pelat C, Falchi A, Carrat F, Mosnier A, Bonmarin I, Turbelin C, Vaux S, van der Werf S, Cohen JM, Lina B, Blanchon T, Hanslik T. Field Effectiveness of Pandemic and 2009-2010 Seasonal Vaccines against 2009-2010 A(H1N1) Influenza: Estimations from Surveillance Data in France. PLoS One. 2011. 6(5):e19621 PubMed PMC 10.1371/journal.pone.0019621
  • Canini L, Andreoletti L, Ferrari P, D'Angelo R, Blanchon T, Lemaitre M, Filleul L, Ferry JP, Desmaizieres M, Smadja S, Valleron AJ, Carrat F. Surgical mask to prevent influenza transmission in households: a cluster randomized trial. PLoS One. 2010. 5(11):e13998 PubMed PMC 10.1371/journal.pone.0013998
  • Carrat F,Pelat C,Levy-Bruhl D,Bonmarin I,Lapidus N. Planning for the next influenza H1N1 season: a modelling study. BMC Infect Dis. 2010. 10:301 PubMed HAL PMC 10.1186/1471-2334-10-301
  • Duval X, van der Werf S, Blanchon T, Mosnier A, Bouscambert-Duchamp M, Tibi A, Enouf V, Charlois-Ou C, Vincent C, Andreoletti L, Tubach F, Lina B, Mentré F, Leport C, BIVIR study group. Efficacy of oseltamivir-zanamivir combination compared to each monotherapy for seasonal influenza: a randomized placebo-controlled trial. PLoS Med. 2010. 7(11):e1000362 PubMed HAL PMC 10.1371/journal.pmed.1000362
  • Hanslik T, Boelle PY, Flahault A. Preliminary estimation of risk factors for admission to intensive care units and for death in patients infected with A(H1N1)2009 influenza virus, France, 2009-2010. PLoS Curr. 2010. 2:RRN1150 PubMed HAL PMC 10.1371/currents.rrn1150
  • Hanslik T, Kerneis S. Alors docteur, dois-je me faire vacciner contre la grippe A ? [So, doctor, should I take the pandemic flu shot]. Rev Med Interne. 2010. 31(1):1-3 PubMed 10.1016/j.revmed.2009.11.005
  • Lemaitre M,Carrat F. Comparative age distribution of influenza morbidity and mortality during seasonal influenza epidemics and the 2009 H1N1 pandemic. BMC Infect Dis. 2010. 10:162 PubMed PMC 10.1186/1471-2334-10-162
  • Valleron AJ, Guidet B. Real-time comparative monitoring of the A/H1N1 pandemic in France. Clin Microbiol Infect. 2010. 16(4):393-6 PubMed 10.1111/j.1469-0691.2010.03166.x
  • Ansart S, Pelat C, Boelle PY, Carrat F, Flahault A, Valleron AJ. Mortality burden of the 1918-1919 influenza pandemic in Europe. Influenza Other Respi Viruses. 2009. 3(3):99-106 PubMed PMC 10.1111/j.1750-2659.2009.00080.x
  • Falchi A, Varesi L, Arena C, Leveque N, Renois F, Blanchon T, Amoros JP, Andreoletti L. Co-circulation of two genetically distinct sub-groups of A/H3N2 influenza strains during the 2006-2007 epidemic season in Corsica Island, France. J Clin Virol. 2009. 45(3):265-8 PubMed HAL 10.1016/j.jcv.2009.05.004
  • Flahault A, de Lamballerie X, Hanslik T. Symptomatic infections less frequent with H1N1pdm than with seasonal strains PLoS Curr. 2009. 1:RRN1140 PubMed HAL PMC 10.1371/currents.rrn1140
  • Pelat C,Turbelin C,Bar-Hen A,Flahault A,Valleron AJ. More diseases tracked by using Google Trends. Emerg Infect Dis. 2009. 15(8):1327-8 PubMed PMC 10.3201/eid1508.090299
  • Turbelin C,Pelat C,Boëlle PY,Lévy-Bruhl D,Carrat F,Blanchon T,Hanslik T. Early estimates of 2009 pandemic influenza A(H1N1) virus activity in general practice in France: incidence of influenza-like illness and age distribution of reported cases. Euro Surveill. 2009. 14(39) PubMed HAL 10.2807/ese.14.39.19341-en
  • Cauchemez S,Valleron AJ,Boëlle PY,Flahault A,Ferguson NM. Estimating the impact of school closure on influenza transmission from Sentinel data. Nature. 2008. 452(7188):750-4 PubMed 10.1038/nature06732
  • Falchi A,Arena C,Andreoletti L,Jacques J,Leveque N,Blanchon T,Lina B,Turbelin C,Dorléans Y,Flahault A,Amoros JP,Spadoni G,Agostini F,Varesi L. Dual infections by influenza A/H3N2 and B viruses and by influenza A/H3N2 and A/H1N1 viruses during winter 2007, Corsica Island, France. J Clin Virol. 2008. 41(2):148-51 PubMed HAL 10.1016/j.jcv.2007.11.003
  • Flahault A. [The epidemiology of influenza pandemics]. Rev Mal Respir. 2008. 25(4):492-6 PubMed HAL 10.1016/s0761-8425(08)71590-0
  • Kernéis S,Grais RF,Boëlle PY,Flahault A,Vergu E. Does the effectiveness of control measures depend on the influenza pandemic profile? PLoS One. 2008. 3(1):e1478 PubMed HAL PMC 10.1371/journal.pone.0001478
  • Carrat F, Flahault A. Influenza vaccine: the challenge of antigenic drift. Vaccine. 2007. 25(39-40):6852-62 PubMed 10.1016/j.vaccine.2007.07.027
  • Colizza V, Barrat A, Barthélemy M, Valleron AJ, Vespignani A. Modeling the worldwide spread of pandemic influenza: baseline case and containment interventions. PLoS Med. 2007. 4(1):e13 PubMed PMC 10.1371/journal.pmed.0040013
  • Denoeud L,Turbelin C,Ansart S,Valleron AJ,Flahault A,Carrat F. Predicting pneumonia and influenza mortality from morbidity data. PLoS One. 2007. 2(5):e464 PubMed PMC 10.1371/journal.pone.0000464
  • Cauchemez S, Boëlle PY, Thomas G, Valleron AJ. Estimating in real time the efficacy of measures to control emerging communicable diseases. Am J Epidemiol. 2006. 164(6):591-7 PubMed 10.1093/aje/kwj274
  • Flahault A. Global monitoring of influenza: potential contribution of national networks from a French perspective. Expert Rev Anti Infect Ther. 2006. 4(3):387-93 PubMed 10.1586/14787210.4.3.387
  • Flahault A, Vergu E, Coudeville L, Grais RF. Strategies for containing a global influenza pandemic. Vaccine. 2006. 24(44-46):6751-5 PubMed HAL 10.1016/j.vaccine.2006.05.079
  • Lavenu A, Leruez-Ville M, Chaix ML, Boelle PY, Rogez S, Freymuth F, Hay A, Rouzioux C, Carrat F. Detailed analysis of the genetic evolution of influenza virus during the course of an epidemic. Epidemiol Infect. 2006. 134(3):514-20 PubMed PMC 10.1017/S0950268805005686
  • Le Menach A, Vergu E, Grais RF, Smith DL, Flahault A. Key strategies for reducing spread of avian influenza among commercial poultry holdings: lessons for transmission to humans. Proc Biol Sci. 2006. 273(1600):2467-75 PubMed HAL PMC 10.1098/rspb.2006.3609
  • Legrand J, Vergu E, Flahault A. Real-time monitoring of the influenza vaccine field effectiveness. Vaccine. 2006. 24(44-46):6605-11 PubMed HAL 10.1016/j.vaccine.2006.05.063
  • Ferguson NM, Cummings DA, Cauchemez S, Fraser C, Riley S, Meeyai A, Iamsirithaworn S, Burke DS. Strategies for containing an emerging influenza pandemic in Southeast Asia. Nature. 2005. 437(7056):209-14 PubMed 10.1038/nature04017
  • Viboud C, Boëlle PY, Cauchemez S, Lavenu A, Valleron AJ, Flahault A, Carrat F. Risk factors of influenza transmission in households. Br J Gen Pract. 2004. 54(506):684-9 PubMed PMC
  • Viboud C, Boëlle PY, Pakdaman K, Carrat F, Valleron AJ, Flahault A. Influenza epidemics in the United States, France, and Australia, 1972-1997. Emerg Infect Dis. 2004. 10(1):32-9 PubMed PMC 10.3201/eid1001.020705
  • Viboud C, Pakdaman K, Boëlle PY, Wilson ML, Myers MF, Valleron AJ, Flahault A. Association of influenza epidemics with global climate variability. Eur J Epidemiol. 2004. 19(11):1055-9 PubMed 10.1007/s10654-004-2450-9
  • Viboud C, Boëlle PY, Carrat F, Valleron AJ, Flahault A. Prediction of the spread of influenza epidemics by the method of analogues. Am J Epidemiol. 2003. 158(10):996-1006 PubMed 10.1093/aje/kwg239
  • Carrat F, Sahler C, Rogez S, Leruez-Ville M, Freymuth F, Le Gales C, Bungener M, Housset B, Nicolas M, Rouzioux C. Influenza burden of illness: estimates from a national prospective survey of household contacts in France. Arch Intern Med. 2002. 162(16):1842-8 PubMed 10.1001/archinte.162.16.1842
  • Flahault A. [Influenza: is it time for mass immunization of healthy infants?]. Rev Epidemiol Sante Publique. 2000. 48(3):311-2 PubMed
  • Carrat F, Tachet A, Rouzioux C, Housset B, Valleron AJ. Evaluation of clinical case definitions of influenza: detailed investigation of patients during the 1995-1996 epidemic in France. Clin Infect Dis. 1999. 28(2):283-90 PubMed 10.1086/515117
  • Bonabeau E, Toubiana L, Flahault A. The geographical spread of influenza. Proc Biol Sci. 1998. 265(1413):2421-5 PubMed PMC 10.1098/rspb.1998.0593
  • Carrat F, Flahault A, Boussard E, Farran N, Dangoumau L, Valleron AJ. Surveillance of influenza-like illness in France. The example of the 1995/1996 epidemic. J Epidemiol Community Health. 1998. 52 Suppl 1:32S-38S PubMed
  • Carrat F, Tachet A, Rouzioux C, Housset B, Valleron AJ. Field investigation of influenza vaccine effectiveness on morbidity. Vaccine. 1998. 16(9-10):893-8 PubMed 10.1016/s0264-410x(97)00307-1
  • Flahault A, Dias-Ferrao V, Chaberty P, Esteves K, Valleron AJ, Lavanchy D. FluNet as a tool for global monitoring of influenza on the Web. JAMA. 1998. 280(15):1330-2 PubMed 10.1001/jama.280.15.1330
  • Toubiana L, Flahault A. A space-time criterion for early detection of epidemics of influenza-like-illness. Eur J Epidemiol. 1998. 14(5):465-70 PubMed 10.1023/a:1007481929237
  • Carrat F, Tachet A, Housset B, Valleron AJ, Rouzioux C. Influenza and influenza-like illness in general practice: drawing lessons for surveillance from a pilot study in Paris, France. Br J Gen Pract. 1997. 47(417):217-20 PubMed PMC
  • Carrat F. Vaccination against influenza in healthy adults. N Engl J Med. 1996. 334(6):403; author reply 40 PubMed
  • Carrat F, Valleron AJ. Faut-il vacciner tous les adultes contre la grippe? Concours Médical. 1996. 1:8-10
  • Carrat F. [Influenza vaccine among the aged]. Rev Epidemiol Sante Publique. 1995. 43(1):99-101 PubMed
  • Carrat F, Flahault A, Diaz C. Grippe Clinique : Une épidémie exceptionnellement tardive. Bull Epidémiol Hebd. 1995. 17:75 Lien
  • Carrat F, Valleron AJ. [Anti-influenza vaccine. Bibliographic review]. Rev Mal Respir. 1994. 11(3):239-55 PubMed
  • Costagliola D. When is the epidemic warning cut-off point exceeded? Eur J Epidemiol. 1994. 10(4):475-6 PubMed 10.1007/BF01719680
  • Flahault A, Deguen S, Valleron AJ. A mathematical model for the European spread of influenza. Eur J Epidemiol. 1994. 10(4):471-4 PubMed 10.1007/BF01719679
  • Hubert B, Watier L, Garnerin P, Richardson S. Meningococcal disease and influenza-like syndrome: a new approach to an old question. J Infect Dis. 1992. 166(3):542-5 PubMed 10.1093/infdis/166.3.542
  • Hubert B, Watier L, Garnerin P, Richardson S. Influence des syndromes grippaux sur l'incidence des infections à méningocoque. Med Mal Infect. 1992. 22(HS):20-2
  • Valleron AJ, Carrat F, Garnerin P. Early detection of epidemic influenza. Lancet. 1992. 339(8784):57-8 PubMed 10.1016/0140-6736(92)90181-2
  • Carrat F, Garnerin P. Epidémie de syndromes grippaux. Bull Epidémiol Hebd. 1991. 50:217 Lien
  • Costagliola D, Flahault A, Galinec D, Garnerin P, Menares J, Valleron AJ. A routine tool for detection and assessment of epidemics of influenza-like syndromes in France. Am J Public Health. 1991. 81(1):97-9 PubMed PMC 10.2105/ajph.81.1.97
  • Menares J, Garnerin P, Hubert B, Valleron AJ. Les syndromes grippaux : France 1988-1990. Bull Epidémiol Hebd. 1990. 24:103-4 Lien
  • Menares J, Garnerin P, Valleron AJ. Syndromes grippaux : Surveillance des syndromes grippaux par un réseau téléinformatique national 1984-1989. REH. 1990. 14:103-4 Lien
  • Menares J, Garnerin P, Valleron AJ. Real time surveillance of influenza-like diseases in france through a national computer network. MMWR Morb Mortal Wkly Rep. 1989. 38(49):855-7 PubMed
  • Menares J, Garnerin P, Valleron AJ. Syndromes grippaux : France 1984-1985 à 1988-1989. Bull Epidémiol Hebd. 1989. 38:157-8 Lien
  • Flahault A, Letrait S, Blin P, Hazout S, Ménarés J, Valleron AJ. Modelling the 1985 influenza epidemic in France. Stat Med. 1988. 7(11):1147-55 PubMed 10.1002/sim.4780071107
  • Menares J, Brunet A, Garnerin P, Valleron AJ. La surveillance téléinformatique des syndromes grippaux par le réseau national de médecins généralistes sentinelles. Bull Epidémiol Hebd. 1988. 27:106-7 Lien
  • Flahault A. Un nouvel indicateur épidémiologique pour détecter le début d'une épidémie. Bull Epidémiol Hebd. 1986. 47:185 Lien
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